Алешин Василий Алексеевич
старший научный сотрудник

Избранные статьи

1. Aleshina Yulia A., Zavileyskiy Lev G., Aleshin Vasily A. (2025) Neanderthal and Denisovan Glutamate Dehydrogenase 2 Evolution and Clinical Significance. International Journal of Molecular Sciences, >>


2. Aleshina Yulia A., Aleshin Vasily A. (2024) Evolutionary Changes in Primate Glutamate Dehydrogenases 1 and 2 Influence the Protein Regulation by Ligands, Targeting and Posttranslational Modifications. International Journal of Molecular Sciences, >>


3. Aleshin Vasily A., Kaehne Thilo, Maslova Maria V., Graf Anastasia V., Bunik Victoria I. (2024) Posttranslational Acylations of the Rat Brain Transketolase Discriminate the Enzyme Responses to Inhibitors of ThDP-Dependent Enzymes or Thiamine Transport. International Journal of Molecular Sciences, >>


4. Aleshin Vasily A., Graf Anastasia V., Artiukhov Artem V., Ksenofontov Alexander L., Zavileyskiy Lev G., Maslova Maria V., Bunik Victoria I. (2023) Pentylenetetrazole-Induced Seizures Are Increased after Kindling, Exhibiting Vitamin-Responsive Correlations to the Post-Seizures Behavior, Amino Acids Metabolism and Key Metabolic Regulators in the Rat Brain. International Journal of Molecular Sciences, >>


5. Алешин В.А., Буник В.И. (2023) Белок-белковые интерфейсы как мишени лекарств: общий для пиридоксаль-5′-фосфат-зависимых ферментов мотив для получения кофермента от его продуцентов. Биохимия, >>


6. Aleshin Vasily A., Bunik Victoria I. (2023) Protein–Protein Interfaces as Druggable Targets: A Common Motif of the Pyridoxal-5′-Phosphate-Dependent Enzymes to Receive the Coenzyme from Its Producers. Biochemistry (Moscow), >>


7. Алешин В.А., Сибирякина Д.A., Казанцев А.В., Граф А.В., Буник В.И. (2023) Ацилирование белков мозга крысы изменяется при специфическом ингибировании пируватдегидрогеназы in vivo. Биохимия, >>


8. Aleshin Vasily A., Sibiryakina Daria A., Kazantsev Alexey V., Graf Anastasia V., Bunik Victoria I. (2023) Acylation of the Rat Brain Proteins is Affected by the Inhibition of Pyruvate Dehydrogenase in vivo. Biochemistry (Moscow), >>


9. Artiukhov Artem V., Aleshin Vasily A., Karlina Irina S., Kazantsev Alexey V., Sibiryakina Daria A., Ksenofontov Alexander L., Lukashev Nikolay V., Graf Anastasia V., Bunik Victoria I. (2022) Phosphonate Inhibitors of Pyruvate Dehydrogenase Perturb Homeostasis of Amino Acids and Protein Succinylation in the Brain. International Journal of Molecular Sciences, >>


10. Zavileyskiy Lev G., Aleshin Vasily A., Kaehne Thilo, Karlina Irina S., Artiukhov Artem V., Maslova Maria V., Graf Anastasia V., Bunik Victoria I. (2022) The Brain Protein Acylation System Responds to Seizures in the Rat Model of PTZ-Induced Epilepsy. International Journal of Molecular Sciences, >>


11. Aleshin Vasily A., Bunik Victoria I., Bruch Eduardo M., Bellinzoni Marco (2022) Structural Basis for the Binding of Allosteric Activators Leucine and ADP to Mammalian Glutamate Dehydrogenase. International Journal of Molecular Sciences, >>


12. Bunik Victoria I., Artiukhov Artem V., Kazantsev Alexey V., Aleshin Vasily A., Boyko Alexandra I., Ksenofontov Alexander L., Lukashev Nikolay V., Graf Anastasia V. (2022) Administration of Phosphonate Inhibitors of Dehydrogenases of 2-Oxoglutarate and 2-Oxoadipate to Rats Elicits Target-Specific Metabolic and Physiological Responses. Frontiers in Chemistry, >>


13. Boyko Alexandra I., Karlina Irina S., Zavileyskiy Lev G., Aleshin Vasily A., Artiukhov Artem V., Kaehne Thilo, Ksenofontov Alexander L., Ryabov Sergey I., Graf Anastasia V., Tramonti Angela, Bunik Victoria I. (2022) Delayed Impact of 2-Oxoadipate Dehydrogenase Inhibition on the Rat Brain Metabolism Is Linked to Protein Glutarylation. Frontiers in Medicine, >>


14. Graf Anastasia V., Maslova Maria V., Artiukhov Artem V., Ksenofontov Alexander L., Aleshin Vasily A., Bunik Victoria I. (2022) Acute Prenatal Hypoxia in Rats Affects Physiology and Brain Metabolism in the Offspring, Dependent on Sex and Gestational Age. International Journal of Molecular Sciences, >>


15. Artiukhov Artem V., Graf Anastasia V., Kazantsev Alexey V., Boyko Alexandra I., Aleshin Vasily A., Ksenofontov Alexander L., Bunik Victoria I. (2022) Increasing Inhibition of the Rat Brain 2-Oxoglutarate Dehydrogenase Decreases Glutathione Redox State, Elevating Anxiety and Perturbing Stress Adaptation. Pharmaceuticals, >>


16. Bunik Victoria, Aleshin Vasily, Nogues Isabel, Kähne Thilo, Parroni Alessia, Contestabile Roberto, Salvo Martino Luigi, Graf Anastasia, Tramonti Angela (2022) Thiamine-dependent regulation of mammalian brain pyridoxal kinase in vitro and in vivo. Journal of Neurochemistry, >>


17. Artiukhov Artem V., Kolesanova Ekaterina F., Boyko Aleksandra I., Chashnikova Anastasiya A., Gnedoy Sergei N., Kaehne Thilo, Ivanova Daria A., Kolesnichenko Alyona V., Aleshin Vasily A., Bunik Victoria I. (2021) Preparation of Affinity Purified Antibodies against ε-Glutaryl-Lysine Residues in Proteins for Investigation of Glutarylated Proteins in Animal Tissues. Biomolecules, >>


18. Aleshin Vasily A., Graf Anastasia V., Artiukhov Artem V., Boyko Alexandra I., Ksenofontov Alexander L., Maslova Maria V., Nogués Isabel, di Salvo Martino L., Bunik Victoria I. (2021) Physiological and Biochemical Markers of the Sex-Specific Sensitivity to Epileptogenic Factors, Delayed Consequences of Seizures and Their Response to Vitamins B1 and B6 in a Rat Model. Pharmaceuticals, >>


19. Aleshin Vasily A., Artiukhov Artem V., Kaehne Thilo, Graf Anastasia V., Bunik Victoria I. (2021) Daytime Dependence of the Activity of the Rat Brain Pyruvate Dehydrogenase Corresponds to the Mitochondrial Sirtuin 3 Level and Acetylation of Brain Proteins, All Regulated by Thiamine Administration Decreasing Phosphorylation of PDHA Ser293. International Journal of Molecular Sciences, >>


20. Aleshin VA, Zhou X., Krishnan S., Karlsson A., Bunik VI (2021) Interplay Between Thiamine and p53/p21 Axes Affects Antiproliferative Action of Cisplatin in Lung Adenocarcinoma Cells by Changing metabolism of 2-oxoglutarate/glutamate. Frontiers in genetics, >>


21. Boyko A., Tsepkova P., Aleshin V., Artiukhov A., Mkrtchyan G., Ksenofontov A., Baratova L., Ryabov S., Graf A., Bunik V. (2021) Severe Spinal Cord Injury in Rats Induces Chronic Changes in the Spinal Cord and Cerebral Cortex Metabolism, Adjusted by Thiamine That Improves Locomotor Performance. Frontiers in Molecular Neuroscience, >>