Лямзаев Константин Геннадьевич

НИИ Физико-химической биологииимени А. Н. Белозерского МГУ

  2. Отделы и лаборатории
  3. Сотрудники

Лямзаев Константин Геннадьевич
ведущий научный сотрудник

Почта
lyamzaev@belozersky.msu.ru

Избранные статьи

  1. Firsov Alexander M., Khailova Ljudmila S., Nazarov Pavel A., Ukraintsev Maxim, Kirsanov Roman S., Kovalchuk Sergei I., Lyamzaev Konstantin G., Panteleeva Alisa A., Korshunova Galina A., Kotova Elena A., Antonenko Yuri N. (2025) 2-Azido-4-nitrophenol is a light-sensitive antibacterial protonophore. Bioelectrochemistry, >>

  2. Antonenko Yuri N., Rudenko Alexander Y., Khailova Ljudmila S., Firsov Alexander M., Kirsanov Roman S., Lyamzaev Konstantin G., Panteleeva Alisa A., Popova Lyudmila B., Mariasina Sofia S., Kotova Elena A., Polshakov Vladimir I. (2025) Cyazofamid-dessulfonamide (CCIM) is an anionic uncoupler of oxidative phosphorylation in mitochondria and a protonophore on lipid membranes. Biochemical and Biophysical Research Communications, >>

  3. Krylova T., Itkis Y., Tsygankova P., Chistol D., Lyamzaev K., Tabakov V., Mikhaylova S., Nikitina N., Rudenskaya G., Murtazina A., A Ivanushkina, D Eliseeva, Y Murakhovskaya, N Sheremet, E Zakharova (2025) Exploring the Phenotypic Heterogeneity and Bioenergetic Profile of the m.13513G>A mtDNA Substitution: A Heteroplasmy Perspective. International Journal of Molecular Sciences, >>

  4. Lyamzaev K.G., Huan H., Panteleeva A.A., Simonyan R.A., Avetisyan A.V., Chernyak B.V. (2024) Exogenous Iron Induces Mitochondrial Lipid Peroxidation, Lipofuscin Accumulation, and Ferroptosis in H9c2 Cardiomyocytes. Biomolecules, >>

  5. Kirsanov Roman S., Khailova Ljudmila S., Krasnov Vladimir S., Firsov Alexander M., Lyamzaev Konstantin G., Panteleeva Alisa A., Popova Lyudmila B., Nazarov Pavel A., Tashlitsky Vadim N., Korshunova Galina A., Kotova Elena A., Antonenko Yuri N. (2024) Spontaneous reversal of small molecule-induced mitochondrial uncoupling: the case of anilinothiophenes. FEBS Journal, >>

  6. Назаров П.А., Зиновкина Л.А., Брезгунова А.А., Лямзаев К.Г., Головин А.В., Каракозова М.В., Котова Е.А., Плотников Е.Ю., Зиновкин Р.А., Скулачев М.В., Антоненко Ю.Н. (2024) Соотношение цитотоксического и антимикробного действия коньюгатов трифенилфосфония с различными производными хинона. Биохимия,

  7. Nazarov Pavel A., Zinovkina Lyudmila A., Brezgunova Anna A., Lyamzaev Konstantin G., Golovin Andrei V., Karakozova Marina V., Kotova Elena A., Plotnikov Egor Yu, Zinovkin Roman A., Skulachev Maxim V., Yuri N.Antonenko (2024) Relationship of Cytotoxic and Antimicrobial Effects of Triphenylphosphonium Conjugates with Various Quinone Derivatives. Biochemistry (Moscow), >>

  8. Kirsanov Roman S., Khailova Ljudmila S., Rokitskaya Tatyana I., Lyamzaev Konstantin G., Panteleeva Alisa A., Nazarov Pavel A., Firsov Alexander M., Iaubasarova Iliuza R., Korshunova Galina A., Kotova Elena A., Antonenko Yuri N. (2024) Synthesis of Triphenylphosphonium-Linked Derivative of 3,5-Ditert-butyl-4-hydroxybenzylidene-malononitrile (SF6847) via Knoevenagel Reaction Yields an Effective Mitochondria-Targeted Protonophoric Uncoupler. ACS Omega, >>

  9. Rokitskaya Tatyana, Kirsanov Roman S., Khailova Ljudmila S., Panteleeva Alisa A., Lyamzaev Konstantin G., Korshunova Galina A., Kotova Elena A., Antonenko Yuri N. (2024) Methylation of Phenyl Rings in Ester‐Stabilized Phosphorus Ylides Vastly Enhances Their Protonophoric Activity. Chembiochem : a European journal of chemical biology, >>

  10. Golenkina Ekaterina A., Viryasova Galina M., Galkina Svetlana I., Kondratenko Natalia D., Gaponova Tatjana V., Romanova Yulia M., Lyamzaev Konstantin G., Chernyak Boris V., Sud’ina Galina F. (2024) Redox processes are major regulators of leukotriene synthesis in neutrophils exposed to bacteria Salmonella typhimurium; the way to manipulate neutrophil swarming. Frontiers in immunology, >>

  11. Челомбитько М.А., Моргунова Г.В., Павлюченкова А.Н., Строчкова Н.Ю., Лямзаев К.Г. (2024) Исследование геропротекторного потенциала производного 7-гидроксикумарина UB3-C10 in vitro. Клиническая геронтология,

  12. Chernyavskij Daniil A., Lyamzaev Konstantin G., Pletjushkina Olga Yu, Chen Fei, Karpukhina Anna, Vassetzky Yegor S., Chernyak Boris V., Popova Ekaterina N. (2024) Mitochondrial fragmentation in early differentiation of human MB135 myoblasts: Role of mitochondrial ROS production in the absence of depolarization. Life Sciences, >>

  13. Huan H., Lyamzaev K.G., Panteleeva A.A., Chernyak B.V. (2024) Mitochondrial lipid peroxidation is necessary but not sufficient for induction of ferroptosis. Frontiers in Cell and Developmental Biology, >>

  14. Lyamzaev K.G., Panteleeva A.A., Simonyan R.A., Armine V.Avetisyan, Boris V.Chernyak (2023) The critical role of mitochondrial lipid peroxidation in ferroptosis: insights from recent studies. Biophysical Reviews, >>

  15. Lyamzaev Konstantin G., Panteleeva Alisa A., Simonyan Ruben A., Avetisyan Armine V., Chernyak Boris V. (2023) Mitochondrial Lipid Peroxidation Is Responsible for Ferroptosis. Cells, >>

  16. Skulachev VP, Vyssokikh MY, Chernyak BV, Averina OA, Andreev-Andrievskiy AA, Zinovkin RA, Lyamzaev KG, Marey MV, Egorov MV, Frolova OJ, Zorov DB, Skulachev MV, Sadovnichii VA (2023) Mitochondrion-targeted antioxidant SkQ1 prevents rapid animal death caused by highly diverse shocks. Scientific reports, >>

  17. Kirsanov Roman S., Khailova Ljudmila S., Rokitskaya Tatyana I., Iaubasarova Iliuza R., Nazarov Pavel A., Panteleeva Alisa A., Lyamzaev Konstantin G., Popova Lyudmila B., Korshunova Galina A., Kotova Elena A., Antonenko Yuri N. (2023) Ester-stabilized phosphorus ylides as protonophores on bilayer lipid membranes, mitochondria and chloroplasts. Bioelectrochemistry, >>

  18. Skulachev V.P., Vyssokikh M.Y., Chernyak B.V., Mulkidjanian A.Y., Skulachev M.V., Shilovsky G.A., Lyamzaev K.G., Borisov V.B., Severin F.F., Sadovnichii V.A. (2023) Six Functions of Respiration: Isn’t It Time to Take Control over ROS Production in Mitochondria, and Aging Along with It?. International Journal of Molecular Sciences, >>

  19. Chelombitko M.A., Morgunova G.V., Strochkova N.Yu, Zinovkin R.A., Pavlyuchenkova A.N., Kondratenko N.D., Lyamzaev K.G. (2023) Comparative analysis of cell senescence induced by the chemotherapeutic agents doxorubicin, cisplatin and arsenic trioxide in human myoblasts. Advances in Gerontology, >>

  20. Zinovkin Roman A., Lyamzaev Konstantin G., Chernyak Boris V. (2023) Current perspectives of mitochondria-targeted antioxidants in cancer prevention and treatment. Frontiers in Cell and Developmental Biology, >>

  21. Chelombitko M.A., Morgunova G.V., Strochkova N.Yu, Lyamzaev K.G. (2023) Geroprotective effect of the mitochondrial-targeted antioxidant SkQBerb in a model of the chronological aging of MB135 human myoblasts. Advances in Gerontology, >>

  22. Челомбитько М.А., Моргунова Г.В., Строчкова Н.Ю., Лямзаев К.Г. (2023) Геропротекторный эффект митохондриально-направленного антиоксиданта SkQBerb в модели хронологического старения миобластов человека MB135. Проблемы геронауки, >>

  23. Krasnov Vladimir S., Kirsanov Roman S., Khailova Ljudmila S., Popova Lyudmila B., Lyamzaev Konstantin G., Firsov Alexander M., Korshunova Galina A., Kotova Elena A., Antonenko Yuri N. (2022) Alkyl esters of 7-hydroxycoumarin-3-carboxylic acid as potent tissue-specific uncouplers of oxidative phosphorylation: Involvement of ATP/ADP translocase in mitochondrial uncoupling. Archives of Biochemistry and Biophysics, >>

  24. Lyamzaev Konstantin G., Zinovkin Roman A., Chernyak Boris V. (2022) Extrusion of mitochondria: garbage clearance or cell‐cell communication signals?. Journal of Cellular Physiology, >>

  25. Шеремет Н.Л., Ронзина И.А., Андреева Н.А., Жоржоладзе Н.В., Мураховская Ю.К., Невиницына Т.А., Шмелькова М.С., Крылова Т.Д., Цыганкова П.Г., Герасимиди Е.С., Лямзаев К.Г., Скулачев М.В., Каргер Е.М. (2022) Электрофизиологические и психофизические исследования в оценке зрительных функций при наследственной оптической нейропатии. Вестник офтальмологии, >>

  26. Chernyak Boris V., Lyamzaev Konstantin G. (2022) Innate Immunity and Phenoptosis. Biochemistry (Moscow), >>

  27. Chernyak Boris V., Lyamzaev Konstantin G., Mulkidjanian Armen Y. (2021) Innate Immunity as an Executor of the Programmed Death of Individual Organisms for the Benefit of the Entire Population. International Journal of Molecular Sciences, >>

  28. Klionsky Daniel J., Lyamzaev Konstantin G., Chernyak Boris V., et al. (2021) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy, >>

  29. Nesterov S.V., Chesnokov Y., Kamyshinsky R., Panteleeva A.A., Lyamzaev K., Vasilov R., Yaguzhinsky L. (2021) Ordered Clusters of the Complete Oxidative Phosphorylation System in Cardiac Mitochondria. International Journal of Molecular Sciences, >>

  30. Lyamzaev Konstantin G., Panteleeva Alisa A., Karpukhina Anna A., Galkin Ivan I., Popova Ekatherina N., Pletjushkina Olga Yu, Bettina Rieger, Busch Karin B., Mulkidjanian Armen Y., Chernyak Boris V. (2020) Novel Fluorescent Mitochondria-Targeted Probe MitoCLox Reports Lipid Peroxidation in Response to Oxidative Stress In Vivo. Oxidative Medicine and Cellular Longevity, >>

  31. Goleva Tatyana N., Lyamzaev Konstantin G., Rogov Anton G., Khailova Ljudmila S., Epremyan Khoren K., Shumakovich Galina P., Domnina Lidia V., Ivanova Olga Yu, Marmiy Natalia V., Zinevich Tatiana V., Esipov Dmitry S., Zvyagilskaya Renata A., Skulachev Vlad (2020) Mitochondria-targeted 1,4-naphthoquinone (SkQN) is a powerful prooxidant and cytotoxic agent. Biochimica et Biophysica Acta - Bioenergetics, >>

  32. Lyamzaev Konstantin G., Sumbatyan Natalia V., Nesterenko Alexey M., Kholina Ekaterina G., Natalia Voskoboynikova, Heinz-Jürgen Steinhoff, Mulkidjanian Armen Y., Chernyak Boris V. (2019) MitoCLox: A Novel Mitochondria-Targeted Fluorescent Probe for Tracing Lipid Peroxidation. Oxidative Medicine and Cellular Longevity, >>

  33. Elena Fetisova, Maria Muntyan, Konstantin Lyamzaev, Boris Chernyak (2019) Therapeutic effect of the mitochondria-targeted antioxidant SkQ1 on the culture model of multiple sclerosis. Oxidative Medicine and Cellular Longevity, >>

  34. Nesterenko A.M., Kholina E.G., Lyamzaev K.G., Mulkidzhanyan A.Y., Chernyak B.V. (2019) Molecular dynamics modeling of the interaction of cationic fluorescent lipid peroxidation-sensitive probes with the mitochondrial membrane. Doklady Biochemistry and Biophysics, >>

  35. Mulkidjanian A.Y., Shalaeva D.N., Lyamzaev K.G., Chernyak B.V. (2018) Could the fission of mitochondria in response to oxidative stress prevent apoptosis?. Biochemistry (Moscow), >>

  36. Lyamzaev KG, Tokarchuk AV, Panteleeva AA, Mulkidjanian AY, Skulachev VP, Chernyak BV (2018) Induction of autophagy by depolarization of mitochondria. Autophagy, >>