Сайт в стадии разработки [Старая версия сайта]
Самый цитируемый биологический институт РФ *

Вартапетян Андрей Борисович

зав. отделом, профессор, доктор химических наук
Контакт
Телефон: 8 (495) 939-41-25
Адрес: корп. Б, комн. 319
Возглавляет отдел: Отдел химии и биохимии нуклеопротеидов
Возглавляет лабораторию: Лаборатория молекулярной биологии гена
Подразделение: Лаборатория молекулярной биологии гена

Область научных интересов: молекулярная и клеточная биология.

Читает лекционный курс «Генетическая инженерия» для студентов факультета биоинженерии и биоинформатики МГУ.

Статьи
  1. Galiullina R.A., Kasperkiewicz P., Chichkova N.V., Szalek A., Serebryakova M.V., Poreba M., Drag M., Vartapetian A.B. (2015) Substrate Specificity and Possible Heterologous Targets of Phytaspase, a Plant Cell Death Protease. J. Biol. Chem., 290 (41): 24806-24815. >>

  2. Chichkova N.V., Galiullina R.A., Beloshistov R.E., Balakireva A.V., Vartapetian A.B. (2014) Phytaspases: Aspartate-Specific Proteases Involved in Plant Cell Death. Russ. J. Bioorg. Chem., 40 (6): 606-611. >>

  3. Dolgikh Y.I., Stepanova A.Y., Trusova S.V., Chichkova N.V., Vartapetian A.B. (2013) Mitochondria-targeted antioxidant provides for enhanced morphogenetic potential in plant tissue cultures. Russ. J. Plant Physiol., 60 (5): 706-712. >>

  4. Fomicheva A.S., Tuzhikov A.I., Beloshistov R.E., Trusova S.V., Galiullina R.A., Mochalova L.V., Chichkova N.V., Vartapetian A.B. (2012) Programmed cell death in plants. Biochem.-Moscow, 77 (13): 1452-1464. >>

  5. Chichkova N.V., Tuzhikov A.I., Taliansky M., Vartapetian A.B. (2012) Plant phytaspases and animal caspases: structurally unrelated death proteases with a common role and specificity. Physiol. Plant., 145 (1): 77-84. >>

  6. Vartapetian A.B., Tuzhikov A.I., Chichkova N.V., Taliansky M., Wolpert T.J. (2011) A plant alternative to animal caspases: subtilisin-like proteases. Cell Death and Differentiation, 18 (8): 1289-1297.

  7. Khutornenko A.A., Roudko V.V., Chernyak B.V., Vartapetian A.B., Chumakov P.M., Evstafieva A.G. (2010) Pyrimidine biosynthesis links mitochondrial respiration to the p53 pathway. Proceedings of the National Academy of Sciences of the United States of America, 107 (29): 12828-12833.

  8. Chichkova N.V., Shaw J., Galiullina R.A., Drury G.E., Tuzhikov A.I., Kim S.H., Kalkum M., Hong T.B., Gorshkova E.N., Torrance L., Vartapetian A.B., Taliansky M. (2010) Phytaspase, a relocalisable cell death promoting plant protease with caspase specificity. EMBO Journal, 29 (6): 1149-1161.

  9. Zakharova N.I., Sokolov V.V., Roudko V.V., Melnikov S.V., Vartapetian A.B., Evstafieva A.G. (2008) Effect of prothymosin alpha and its mutants on the activity of the p53 tumor suppressor. Molecular Biology, 42 (4): 598-608.

  10. Melnikov S.V., Evstafieva A.G., Vartapetian A.B. (2007) Interaction with Keap1 does not lead to ubiquitination and degradation of prothymosin alpha. Molecular Biology, 41 (5): 790-796.

  11. Reavy B., Bagirova S., Chichkova N.V., Fedoseeva S.V., Kim S.H., Vartapetian A.B., Taliansky M.E. (2007) Caspase-resistant VirD2 protein provides enhanced gene delivery and expression in plants. Plant Cell Reports, 26 (8): 1215-1219.

  12. Evstafieva A.G., Karapetian R.N., Rubtsov Y.P., Filonov G.S., Abaeva I.S., Fateeva T.V., Melnikov S.V., Chichkova N.V., Vartapetian A.B. (2005) Novel functions of the well-known protein-prothymosin alpha is involved in protection of cells against apoptosis and oxidative stress. Molecular Biology, 39 (5): 729-745.

  13. Karapetian R.N., Evstafieva A.G., Abaeva I.S., Chichkova N.V., Filonov G.S., Rubtsov Y.P., Sukhacheva E.A., Melnikov S.V., Schneider U., Wanker E.E., Vartapetian A.B. (2005) Nuclear oncoprotein prothymosin alpha is a partner of Keap1: Implications for expression of oxidative stress-protecting genes. Molecular and Cellular Biology, 25 (3): 1089-1099.

  14. Romanova L.I., Belov G.A., Lidsky P.V., Tolskaya E.A., Kolesnikova M.S., Evstafieva A.G., Vartapetian A.B., Egger D., Bienz K., Agol V.I. (2005) Variability in apoptotic response to poliovirus infection. Virology, 331 (2): 292-306.

  15. Nomura S., Baxter T., Yamaguchi H., Leys C., Vartapetian A.B., Fox J.G., Lee J.R., Wang T.C., Goldenring J.R. (2004) Spasmolytic polypeptide expressing metaplasia to preneoplasia in H-felis-infected mice. Gastroenterology, 127 (2): 582-594.

  16. Yang C.H., Murti A., Baker S.J., Frangou-lazaridis M., Vartapetian A.B., Murti K.G., Pfeffer L.M. (2004) Interferon induces the interaction of prothymosin-alpha with STAT3 and results in the nuclear translocation of the complex. Experimental Cell Research, 298 (1): 197-206.

  17. Chichkova N.V., Kim S.H., Titova E.S., Kalkum M., Morozov V.S., Rubtsov Y.P., Kalinina N.O., Taliansky M.E., Vartapetian A.B. (2004) A plant caspase-like protease activated during the hypersensitive response. Plant Cell, 16 (1): 157-171.

  18. Evstafieva A.G., Belov G.A., Rubtsov Y.P., Kalkum M., Joseph B., Chichkova N.V., Sukhacheva E.A., Bogdanov A.A., Pettersson R.F., Agol V.I., Vartapetian A.B. (2003) Apoptosis-related fragmentation, translocation, and properties of human prothymosin alpha. Experimental Cell Research, 284 (2): 211-223.

  19. Markova O.V., Evstafieva A.G., Mansurova S.E., Moussine S.S., Palamarchuk L.A., Pereverzev M.O., Vartapetian A.B., Skulachev V.P. (2003) Cytochrome c is transformed from anti- to pro-oxidant when interacting with truncated oncoprotein prothymosin alpha. Biochimica et Biophysica Acta-Bioenergetics, 1557 (1): 109-117.

  20. Sukhacheva E.A., Evstafieva A.G., Fateeva T.V., Shakulov V.R., Efimova N.A., Karapetian R.N., Rubtsov Y.P., Vartapetian A.B. (2002) Sensing prothymosin alpha origin, mutations and conformation with monoclonal antibodies. Journal of Immunological Methods, 266 (1): 185-196.

  21. Babkina O.V., Evstafieva A.G., Chichkova N.V., Vartapetian A.B., Muller S., Baskunov V.B., Petrauskene O.V., Kochetkov S.N., Gromova E.S. (2000) Recombinant components of the EcoRII restriction-modification system: Restriction endonuclease can interact with DNA center dot RNA duplexes. Molecular Biology, 34 (6): 913-920.

  22. Shakulov V.R., Vorobjev I.A., Rubtsov Y.P., Chichkova N.V., Vartapetian A.B. (2000) Interaction of yeast importin alpha with the NLS of prothymosin alpha is insufficient to trigger nuclear uptake of cargos. Biochemical and Biophysical Research Communications, 274 (2): 548-552.

  23. Chichkova N.V., Evstafieva A.G., Lyakhov I.G., Tsvetkov A.S., Smirnova T.A., Karapetian R.N., Karger E.M., Vartapetian A.B. (2000) Divalent metal cation binding properties of human prothymosin alpha. European Journal of Biochemistry, 267 (15): 4745-4752.

  24. Evstafieva A.G., Belov G.A., Kalkum M., Chichkova N.V., Bogdanov A.A., Agol V.I., Vartapetian A.B. (2000) Prothymosin alpha fragmentation in apoptosis. FEBS Letters, 467 (2): 150-154.

  25. Lukashev D.E., Chichkova N.V., Vartapetian A.B. (1999) Multiple tRNA attachment sites in prothymosin alpha. FEBS Letters, 451 (2): 118-124.

  26. Rubtsov Y.P., Zolotukhin A.S., Vorobjev I.A., Chichkova N.V., Pavlov N.A., Karger E.M., Evstafieva A.G., Felber B.K., Vartapetian A.B. (1997) Mutational analysis of human prothymosin alpha reveals a bipartite nuclear localization signal. FEBS Letters, 413 (1): 135-141.

  27. Rubtsov Y.P., Vartapetyan A.B. (1995) New intronless genes of human prothymosin alpha family. Molecular Biology, 29 (6): 787-790.

  28. Evstafieva A.G., Chichkova N.V., Makarova T.N., Vartapetian A.B., Vasilenko A., Abramov V.M., Bogdanov A.A. (1995) Overproduction in Escherichia-Coli, Purification and Properties of Human Prothymosin-Alpha. European Journal of Biochemistry, 231 (3): 639-643.

  29. Vartapetyan A.B. (1992) Myc and Prothymosin-Alpha Proteins and Cell-Division. Biochemistry-Moscow, 57 (3): 323.