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The most cited biological Institute in Russia *

Варфоломеев Сергей Дмитриевич

чл.-кор. РАН, профессор, доктор химических наук
Contact
Head of the laboratory: Лаборатория полиферментных систем
Belongs to: Лаборатория полиферментных систем
Профессор Московского университета, доктор химических наук, заведующий кафедрой химической энзимологии МГУ им М.В. Ломоносова Работает в области химии и физико-химической биологии.
Recent Papers
  1. Demina O.V., Varfolomeev S.D., Lukin A.Y., Laptev A.V., Shvets V.I., Khodonov A.A., Khitrina L.V., Gromov S.P., Vedernikov A.I., Barachevsky V.A., Strokach Y.P., Alfimov M.V., Lugtenburg J. (2005) Investigation of the spectral properties of the crowned retinals and bacteriorhodopsin analogs. Molecular Crystals and Liquid Crystals, 431: 509-514.

  2. Ilyina A.D., Zaitsev S.V., Grishina I.A., Varfolomeev S.D. (1998) Kinetics of homeostatic behavior of receptor-enzyme systems under the action of physiologically active compounds. Biosystems, 45 (1): 77-85.

  3. Ilyina A.D., Zaitsev S.V., Grishina I.A., Varfolomeev S.D. (1998) Kinetics of homeostatic behavior of receptor-enzyme systems under the action of physiologically active compounds. Biosystems, 45 (1): 77-85.

  4. Mirzoeva O.K., Sudina G.F., Pushkareva M.A., Varfolomeev S.D. (1995) Competitive inhibition of the 5-lipoxygenase-catalysed linoleate oxidation by arachidonic and 5-hydroperoxy-eicosatetraenoic acids. FEBS Letters, 377 (3): 306-308.

  5. Demina O.V., Vrzheshch P.V., Khodonov A.A., Kozlovskii V.I., Varfolomeev S.D. (1995) Synthesis of substituted pyridylisoxazoles and their 4,5-dihydro analogs - Novel inhibitors of thrombocyte aggregation. Bioorganicheskaya Khimiya, 21 (12): 933-940.

  6. Mirzoeva O.K., Sudina G.F., Pushkareva M.A., Korshunova G.A., Sumbatyan N.V., Varfolomeev S.D. (1995) Lipophilic Derivatives of Caffeic Acid As Lipoxygenase Inhibitors with Antioxidant Properties. Bioorganicheskaya Khimiya, 21 (2): 143-151.

  7. Efanov A.M., Koshkin A.A., Sazanov L.A., Borodulina O.I., Varfolomeev S.D., Zaitsev S.V. (1994) Inhibition of the Respiratory Burst in Mouse Macrophages by Ultra-Low Doses of An Opioid Peptide Is Consistent with A Possible Adaptation Mechanism. FEBS Letters, 355 (2): 114-116.

  8. Mevkh A.T., Miroshnikov K.A., Igumnova N.D., Varfolomeev S.D. (1993) Prostaglandin-H Synthase - Chemical Modification of Histidine-Residues in Deferent Forms of the Enzyme with Diethyl Pyrocarbonate. Biochemistry-Moscow, 58 (10): 1154-1158.

  9. Sudina G.F., Mirzoeva O.K., Pushkareva M.A., Korshunova G.A., Sumbatyan N.V., Varfolomeev S.D. (1993) Caffeic Acid Phenethyl Ester As A Lipoxygenase Inhibitor with Antioxidant Properties. FEBS Letters, 329 (1): 21-24.

  10. Sergeeva M.G., Terentjeva I.V., Mevkh A.T., Varfolomeev S.D. (1993) Direct Influence of Morphine on the Release of Arachidonic-Acid and Its Metabolites. FEBS Letters, 323 (1): 163-165.

  11. Mevkh A.T., Miroshnikov K.A., Igumnova N.D., Varfolomeev S.D. (1993) Prostaglandin-H Synthase - Inactivation of the Enzyme in the Course of Catalysis Is Accompanied by Fast and Dramatic Changes in Protein-Structure. FEBS Letters, 321 (2): 205-208.

  12. Zaitsev S.V., Ilina A.D., Klodt P.M., Varfolomeev S.D., Yukhananov R.Y. (1992) Heterogeneity of Mu-and Delta-Opioid Binding-Sites in Murine Cerebral-Cortex - Selective Increase in Affinity of Superhigh-Affinity Delta-Binding Sites After Long-Term Administration of Morphine. Biochemistry-Moscow, 57 (8): 859-862.

  13. Vrzheshch P.V., Tatarintsev A.V., Orlova E.V., Ershov D.E., Varfolomeev S.D. (1992) Kinetics of Merthiolate-Induced Aggregation of Human Platelets. Biochemistry-Moscow, 57 (3): 307-316.

  14. Zaitsev S.V., Koshkin A.A., Izumrudova I.I., Varfolomeev S.D. (1992) A Study of the Kinetics of the Interaction of Spiperone with Binding-Sites on Human Mononuclear-Cells - Existence of A Heterogeneous Population of Spiperone Binding-Sites. Journal of Neuroimmunology, 36 (2): 225-229.

  15. Zaitsev S.V., Sazanov L.A., Koshkin A.A., Sudina G.F., Varfolomeev S.D. (1991) Respiratory Burst Inhibition in Human Neutrophils by Ultra-Low Doses of [D-Ala2]Methionine Enkephalinamide. FEBS Letters, 291 (1): 84-86.

  16. Sudina G.F., Tatarintsev A.V., Koshkin A.A., Zaitsev S.V., Fedorov N.A., Varfolomeev S.D. (1991) The Role of Adhesive Interactions and Extracellular-Matrix Fibronectin from Human Polymorphonuclear Leukocytes in the Respiratory Burst. Biochimica et Biophysica Acta, 1091 (3): 257-260.

  17. Sudina G.F., Tatarintsev A.V., Koshkin A.A., Zaitsev S.V., Fedorov N.A., Varfolomeev S.D. (1991) The Role of Adhesive Interactions and Extracellular-Matrix Fibronectin from Human Polymorphonuclear Leukocytes in the Respiratory Burst. Biochimica et Biophysica Acta, 1091 (3): 257-260.

  18. Sudina G.F., Kobelkov G.M., Barskii O.A., Varfolomeev S.D. (1990) Kinetic Scheme of the Action of 5-Lipoxygenase from Human Neutrophils. Biochemistry-Moscow, 55 (10): 1341-1353.

  19. Sobirov M.M., Khalikov S.K., Zaitsev S.V., Saidov S.S., Varfolomeev S.D. (1990) Synthesis and Investigation of Opioid Activity of Bijunctional Neuropeptide Analogs Involving the Mu-Ligands and Delta-Ligands. Vestnik Moskovskogo Universiteta Seriya 2 Khimiya, 31 (3): 321-323.

  20. Sklyankina O.A., Kurochkin I.N., Keldysh P.L., Zaitsev S.V., Varfolomeev S.D. (1988) Kinetic-Model of the Interaction of Stable Gtp Analogs with the Opioid Receptor System. Biochemistry-Moscow, 53 (2): 171-178.

  21. Kurochkin I.N., Zaitsev S.V., Belousov A.S., Sklyankina O.A., Varfolomeev S.D. (1988) Physicochemical Investigation of A Heterogeneous Population of Opioid Receptors. Biochemistry-Moscow, 53 (1): 34-45.

  22. Varfolomeev S.D. (1987) Desensitization As A Reflection of Receptor-Enzyme System in the Course of the Reaction - A Kinetic-Model of the Process. Biochemistry-Moscow, 52 (2): 276-286.