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The most cited biological Institute in Russia *

Vadim I. Agol

correspondent member of RAS and RAMS, professor, D.Biol.Sc.
Telephone: 8(498) 540-90-26
Address: Moskovskaya region, 142782, Kievskoe shosse, 27 km, Institute of poliomyelitis, for V.I.Agol
Fax: (498) 549-61-60
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it.
Head of the department: Department of virus-cell interactions
Belongs to: Department of virus-cell interactions
Professor of the Department of Virology at the Biology Faculty MSU; chief researcher of M.P. Chumakov Institute of Poliomyelitis and Viral Encephalitis.
Recent Papers
  1. Agol V.I. (2012) Cytopathic effects: virus-modulated manifestations of innate immunity?. Trends Microbiol., 20 (12): 570-576. >>

  2. Agol V.I., Gmyl A.P. (2010) Viral security proteins: counteracting host defences. Nature Reviews Microbiology, 8: 867-878. >>

  3. Romanova L.I., Lidsky P.V., Kolesnikova M.S., Fominykh K.V., Gmyl A.P., Sheval E.V., Hato S.V., Van Kuppeveld F.J.M., Agol V.I. (2009) Antiapoptotic Activity of the Cardiovirus Leader Protein, a Viral “Security” Protein. J. Virol., 83 (14): 7273–7284. >>

  4. Yakovenko M.L., Korotkova E.A., Ivanova O.E., Eremeeva T.P., Samoilovich E., Uhova I., Gavrilin G.V., Agol V.I. (2009) Evolution of the Sabin vaccine into pathogenic derivatives without appreciable changes in antigenic properties: need for improvement of current poliovirus surveillance. Journal of Virology, 83 (7): 3402-3406. >>

  5. Chumakov K., Ehrenfeld E., Wimmer E., Agol V.I. (2007) Vaccination against polio should not be stopped. Nature Reviews Microbiology, 5: 952-958. >>

  6. Dmitrieva T.M., Alexeevski A.V., Shatskaya G.S., Tolskaya E.A., Gmyl A.P., Khitrina E.V., Agol V.I. (2007) Significance of the C-terminal amino acid residue in mengovirus RNA-dependent RNA polymerase. Virology, 365 (1): 79-91.

  7. Yakovenko M.L., Cherkasova E.A., Rezapkin G.V., Ivanova O.E., Ivanov A.P., Eremeeva T.P., Baykova O.Y., Chumakov K.M., Agol V.I. (2006) Antigenic evolution of vaccine-derived polioviruses: Changes in individual epitopes and relative stability of the overall immunological properties. Journal of Virology, 80 (6): 2641-2653.

  8. Romanova L.I., Belov G.A., Lidsky P.V., Tolskaya E.A., Kolesnikova M.S., Evstafieva A.G., Vartapetian A.B., Egger D., Bienz K., Agol V.I. (2005) Variability in apoptotic response to poliovirus infection. Virology, 331 (2): 292-306.

  9. Cherkasova E.A., Yakovenko M.L., Rezapkin G.V., Korotkova E.A., Ivanova O.E., Eremeeva T.P., Krasnoproshina L.I., Romanenkova N.I., Rozaeva N.R., Sirota L., Agol V.I., Chumakov K.M. (2005) Spread of vaccine-derived poliovirus from a paralytic case in an immunodeficient child: an insight into the natural evolution of oral polio vaccine. Journal of Virology, 79 (2): 1062-1070.

  10. Belov G.A., Lidsky P.V., Mikitas O.V., Egger D., Lukyanov K.A., Bienz K., Agol V.I. (2004) Bidirectional increase in permeability of nuclear envelope upon poliovirus infection and accompanying alterations of nuclear pores. Journal of Virology, 78 (18): 10166-10177 . >>

  11. Kew O.M., Wright P.F., Agol V.I., Delpeyroux F., Shimizu H., Nathanson N., Pallansch M.A. (2004) Circulating vaccine-derived polioviruses: current state of knowledge. Bulletin of the World Health Organization, 82 (1): 16-23.

  12. Korotkova E.A., Park R., Cherkasova E.A., Lipskaya G.Y., Chumakov K.M., Feldman E.V., Kew O.M, Agol V.I. (2003) Retrospective analysis of a local cessation of vaccination against poliomyelitis: a possible scenario for the future. Journal of Virology, 77 (23): 12460-5. >>

  13. Gmyl A.P., Korshenko S.A., Belousov E.V., Khitrina E.V., Agol V.I. (2003) Nonreplicative homologous RNA recombination: Promiscuous joining of RNA pieces?. RNA, 9 (10): 1221-1231. >>

  14. Cherkasova E., Laassri M., Chizhikov V., Korotkova E., Dragunsky E., Agol V.I., Chumakov K. (2003) Microarray analysis of evolution of RNA viruses: Evidence of circulation of virulent highly divergent vaccine-derived polioviruses. Proceedings of the National Academy of Sciences of the United States of America, 100 (16): 9398-9403.

  15. Evstafieva A.G., Belov G.A., Rubtsov Y.P., Kalkum M., Joseph B., Chichkova N.V., Sukhacheva E.A., Bogdanov A.A., Pettersson R.F., Agol V.I., Vartapetian A.B. (2003) Apoptosis-related fragmentation, translocation, and properties of human prothymosin alpha. Experimental Cell Research, 284 (2): 211-223.

  16. Belov G.A., Romanova L.I., Tolskaya E.A., Kolesnikova M.S., Lazebnik Y.A., Agol V.I. (2003) The Major Apoptotic Pathway Activated and Suppressed by Poliovirus. Journal of Virology, 77 (1): 45-56. >>

  17. Cherkasova E.A., Korotkova E.A., Yakovenko M.L., Ivanova O.E., Eremeeva T.P., Chumakov K.M., Agol V.I. (2002) Long-term circulation of vaccine-derived poliovirus that causes paralytic disease. Journal of Virology, 76 (13): 6791-6799.

  18. Pestova T.V., Kolupaeva V.G., Lomakin I.B., Pilipenko E.V., Shatsky I.N., Agol V.I., Hellen C.U.T. (2001) Molecular mechanisms of translation initiation in eukaryotes. Proceedings of the National Academy of Sciences of the United States of America, 98 (13): 7029-7036.

  19. Pilipenko E.V., Pestova T.V., Kolupaeva V.G., Khitrina E.V., Poperechnaya A.N., Agol V.I., Hellen C.U.T. (2000) A cell cycle-dependent protein serves as a template-specific translation initiation factor. Genes and Development, 14 (16): 2028-2045. >>

  20. Gavrilin G.V., Cherkasova E.A., Lipskaya G.Y., Kew O.M., Agol V.I. (2000) Evolution of circulating wild poliovirus and of vaccine-derived poliovirus in an immunodeficient patient: a unifying model. Journal of Virology, 74 (16): 7381-7390.

  21. Evstafieva A.G., Belov G.A., Kalkum M., Chichkova N.V., Bogdanov A.A., Agol V.I., Vartapetian A.B. (2000) Prothymosin alpha fragmentation in apoptosis. FEBS Letters, 467 (2): 150-154.

  22. Gmyl A.P, Belousov E V., Maslova S.V., Khitrina E.V., Chetverin A., Agol V.I. (1999) Nonreplicative RNA recombination in poliovirus. Journal of Virology, 73 (11): 8958-8965. >>

  23. Lipskaya G.Y., Chervonskaya E.A., Belova G.I., Maslova S.V., Kutateladze T.N., Drozdov S.G., Mulders M., Pallansch M.A., Kew O.M., Agol V.I. (1995) Geographical Genotypes (Geotypes) of Poliovirus Case Isolates from the Former Soviet-Union - Relatedness to Other Known Poliovirus Genotypes. Journal of General Virology, 76: 1687-1699.

  24. Tolskaya E.A., Romanova L.I., Kolesnikova M.S., Ivannikova T.A., Smirnova E.A., Raikhlin N.T., Agol V.I. (1995) Apoptosis-Inducing and Apoptosis-Preventing Functions of Poliovirus. Journal of Virology, 69 (2): 1181-1189.

  25. Pilipenko E.V., Gmyl A.P., Maslova S.V., Belov G.A., Sinyakov A N., Huang M., Brown T.D.K., Agol V.I. (1994) Starting Window, a Distinct Element in the Cap-independent Internal Initiation of Translation on Picornaviral RNA. Journal of Molecular Biology, 241 (3): 398–414. >>

  26. Gmyl A.P., Pilipenko E.V., Maslova S.V., Belov G.A., Agol V.I. (1993) Functional and Genetic Plasticities of the Poliovirus Genome - Quasi-Infectious RNAs Modified in the 5'-Untranslated Region Yield A Variety of Pseudorevertants. Journal of Virology, 67 (10): 6309-6316.

  27. Cho M.W., Richards O.C., Dmitrieva T.M., Agol V., Ehrenfeld E. (1993) RNA Duplex Unwinding Activity of Poliovirus RNA-Dependent RNA-Polymerase 3Dpol. Journal of Virology, 67 (6): 3010-3018.

  28. Teterina N.L., Kean K.M., Gorbalenya A.E., Agol V.I., Girard M. (1992) Analysis of the Functional-Significance of Amino-Acid-Residues in the Putative Ntp-Binding Pattern of the Poliovirus-2C Protein. Journal of General Virology, 73: 1977-1986.

  29. Pilipenko E.V., Gmyl A.P., Maslova S.V., Svitkin Y.V., Sinyakov A.N., Agol V.I. (1992) Prokaryotic-like cis element in the cap-independent internal initiation of translation on picornavirus RNA. Cell, 68 (1): 119-131. >>

  30. Pilipenko E.V., Maslova S.V., Sinyakov A.N., Agol V.I. (1992) Towards identification of cis-acting elements involved in the replication of enterovirus and rhinovirus RNAs: a proposal for the existence of tRNA-like terminal structures. Nucleic Acids Research, 20 (7): 1739-1745. >>

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